Design, troubleshooting, qualification and conduct of ligand-binding assays (eg., MSD, Gyrolab, ELISAs) to support biotherapeutic programs.
Deliver concentration and immunogenicity data to BioMedicine Design Project Leads and other BioTX partners.
Design, develop and implement ligand-binding assays (e.g., MSD, Gyrolab, ELISA) to measure protein concentration of drug and/or biomarker and detect the presence of anti-drug antibody in a fast paced and dynamic environment.
Perform data analysis and interpretation and draw conclusions regarding progress and results of work, utilizing the data for appropriate decision making.
Gather input from colleagues, literature, and additional resources to assist in project advancement.
BSc with 3+ years relevant experience, with a focus on ligand binding assay development.
Ligand binding assay (e.g., (ELISA) experience)
Proven ability to generate high quality data against challenging timelines
Industry experience with a focus in biotherapeutics and a strong record of scientific achievement
Proven track record in the area of biotherapeutics bioanalysis with understanding of a broad range of bioanalytical platforms.
Knowledge and hands-on experience developing ligand-binding assays, utilizing various platforms and demonstrated analytical problem-solving skills.
Broad understanding and skill in areas of bioanalytical laboratory techniques for biotherapeutics (knowledge of ligand-binding assays is essential.
Proven presentation skills.
Proven ability to generate high quality data against challenging timelines.
Ability to communicate across site and discipline to enable maximum impact of bioanalytical science.
Knowledge of biotherapeutic structure, pharmacology, disposition and immunogenicity and the impact on assay selection.
Ability to author technical documents such as data summary reports and analytical procedures.
Collaborative skills and effective partnering skills in a complex, multi-discipline organizational model.
Strong organizational and time management skills in order to balance working on multiple projects in parallel.